GPP 78 hydrochloride

GPP 78 hydrochloride is a potent Nampt inhibitor (IC50 = 3 nM for NAD depletion) that induces autophagy and cytotoxicity in neuroblastoma cells like SH-SY5Y (IC50 = 3.8 nM) . This small molecule is utilized in cancer research, particularly for studying autophagy-mediated cell death and inflammation in both cellular and animal models.