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GSK 143

This small molecule is a potent Syk inhibitor (pIC50 = 7.5) that also suppresses phosphorylated Erk (pIC50 = 7.1) . It reduces cell number and viability in chronic lymphocytic leukemia (CLL) cell lines in vitro, making it a useful research tool for studying B-cell receptor signaling and hematological malignancies.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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