CAY10448
Capsaicin, the lipophilic compound responsible for the pungency of chili peppers, activates the TRPV1 (VR1) ion channel. CAY10448 is a potent iodinated nonivamide derivative that antagonizes this receptor with an IC50 of ~10 nM. This antagonist is widely used in vitro and in vivo to study TRPV1-mediated pain, neurogenic inflammation, and thermoregulation.
Product Specifications
CAS Number
1177195-52-6
Smiles
C (NC (CCCCCCC (C) C) =O) C1=CC (OC) =C (O) C=C1I
Molecular Formula
C18H28INO3
Molecular Weight
433.32
Storage Conditions
-20°C
Notes
For research use only.
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