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CAY10448

Capsaicin, the lipophilic compound responsible for the pungency of chili peppers, activates the TRPV1 (VR1) ion channel. CAY10448 is a potent iodinated nonivamide derivative that antagonizes this receptor with an IC50 of ~10 nM. This antagonist is widely used in vitro and in vivo to study TRPV1-mediated pain, neurogenic inflammation, and thermoregulation.

Product Specifications

CAS Number

1177195-52-6

Smiles

C (NC (CCCCCCC (C) C) =O) C1=CC (OC) =C (O) C=C1I

Molecular Formula

C18H28INO3

Molecular Weight

433.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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