CAY10719
CAY10719 is a potent and selective ABCG2 inhibitor (IC50 = 0.23 μM) that reverses multidrug resistance to chemotherapeutics like SN-38 in vitro. Its ability to suppress ABCG2 ATPase activity makes it a valuable research tool for studying transporter function and overcoming drug efflux in cancer models.
Product Specifications
CAS Number
1942919-63-2
Field of Research
Pharmacology & Drug Discovery
Smiles
C (=O) (N1C (C2=C (C=3C (N2) =CC=CC3) CC1) C4=CC (Cl) =C (Cl) C=C4) C5=CC=C (OC) C=C5
Molecular Formula
C25H20Cl2N2O2
Molecular Weight
451.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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