TAK-700 salt
TAK-700 salt is a highly selective small molecule inhibitor of human 17,20-lyase (CYP17A1), exhibiting potent activity with an IC50 of 38 nM. It demonstrates >1000-fold selectivity over related CYPs like CYP11B1 and CYP3A4. This inhibitor is a valuable research tool for studying androgen biosynthesis in prostate cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
426219-53-6
Field of Research
Epigenetics & Chromatin
Smiles
O[C@@H] ([C@H] (O) C (=O) Nc1ccccc1) C (O) =O.CNC (=O) c1ccc2cc (ccc2c1) [C@@]1 (O) CCn2cncc12
Molecular Formula
C28H28N4O7
Molecular Weight
532.553
Storage Conditions
-20°C
Notes
For research use only.
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