TAK-700 salt

TAK-700 salt is a highly selective small molecule inhibitor of human 17,20-lyase (CYP17A1), exhibiting potent activity with an IC50 of 38 nM. It demonstrates >1000-fold selectivity over related CYPs like CYP11B1 and CYP3A4. This inhibitor is a valuable research tool for studying androgen biosynthesis in prostate cancer models, both in vitro and in vivo.