JNJ-55308942
JNJ-55308942 is a potent, selective, and brain-penetrant P2X7 receptor antagonist, exhibiting nanomolar affinity and inhibitory activity for both human and rat isoforms. This compound is a valuable research tool for investigating the role of P2X7 in neuroinflammation, pain, and mood disorders in both cellular and animal models.
Product Specifications
CAS Number
2166558-11-6
Product Name Alternative
JNJ55308942, JNJ-55308942, JNJ 55308942, P2XReceptor, P2X Receptor, P2X7
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.94% (May vary between batches)
Solubility
DMSO:145 mg/mL (340.92 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.4 mM)
Smiles
C[C@H]1Cc2c (CN1C (=O) c1ccnc (c1F) C (F) (F) F) nnn2-c1ncc (F) cn1
Molecular Formula
C17H12F5N7O
Molecular Weight
425.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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