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JNJ-55308942

JNJ-55308942 is a potent, selective, and brain-penetrant P2X7 receptor antagonist, exhibiting nanomolar affinity and inhibitory activity for both human and rat isoforms. This compound is a valuable research tool for investigating the role of P2X7 in neuroinflammation, pain, and mood disorders in both cellular and animal models.

Product Specifications

CAS Number

2166558-11-6

Product Name Alternative

JNJ55308942, JNJ-55308942, JNJ 55308942, P2XReceptor, P2X Receptor, P2X7

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.94% (May vary between batches)

Solubility

DMSO:145 mg/mL (340.92 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.4 mM)

Smiles

C[C@H]1Cc2c (CN1C (=O) c1ccnc (c1F) C (F) (F) F) nnn2-c1ncc (F) cn1

Molecular Formula

C17H12F5N7O

Molecular Weight

425.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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