M 084 hydrochloride

This compound is a potent and selective blocker of TRPC4/5 channels (IC50 3.7-10.3 μM and 8.2 μM, respectively), with weaker activity against TRPC3. It demonstrates rapid antidepressant and anxiolytic effects in animal models, making it a valuable research tool for studying mood disorders and TRPC channel physiology in vitro and in vivo.