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Glucocorticoid receptor agonist-1

Glucocorticoid receptor agonist-1 is a high-affinity synthetic ligand for the GR, exhibiting potent agonist activity with an IC50 of 2.8 nM. It is a valuable research tool for studying glucocorticoid receptor signaling and its roles in inflammation, metabolism, and stress response in both cellular and animal models.

Product Specifications

CAS Number

2166375-82-0

Product Name Alternative

ADC Cytotoxin, ADCCytotoxin, Glucocorticoid Receptor, Glucocorticoid receptor agonist 1, Glucocorticoid receptor agonist1, Glucocorticoid receptor agonist-1, GlucocorticoidReceptor

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

99.16% (May vary between batches)

Solubility

DMSO:50 mg/mL (87.77 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (4.39 mM)

Smiles

[H][C@]1 (O[C@]2 ([H]) C[C@@]3 ([H]) [C@]4 ([H]) CCC5=CC (=O) C=C[C@]5 (C) [C@@]4 ([H]) [C@@H] (O) C[C@]3 (C) [C@@]2 (O1) C (=O) CO) c1ccc (Cc2cccc (N) c2) cc1

Molecular Formula

C35H39NO6

Molecular Weight

569.69

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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