LEO 39652
LEO 39652 is a potent dual-soft PDE4 inhibitor, showing high activity against PDE4A-D (IC50 1.2-3.8 nM) and TNF-α (IC50 6.0 nM) . Its profile supports topical research for inflammatory skin conditions like atopic dermatitis, with utility in both cellular and preclinical animal models of inflammation.
Product Specifications
CAS Number
1445656-91-6
Field of Research
Metabolism Research
Smiles
COc1ccc (-c2ccc3C (=O) OCc3c2) n2nc (nc12) C1 (CC1) C (=O) OCC (C) C
Molecular Formula
C23H23N3O5
Molecular Weight
421.45
Storage Conditions
-20°C
Notes
For research use only.
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