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ML-309 (hydrochloride)

ML-309 is a reversible and selective small-molecule inhibitor of the mutant IDH1R132H enzyme, exhibiting potent activity against the mutant form over wild-type IDH1. It effectively suppresses 2-HG production in glioblastoma cells and is a valuable research tool for studying IDH1-mutant cancers in both cellular and animal models.

Product Specifications

CAS Number

1355327-02-4

Smiles

Cl.Cc1ccccc1C (N (C (=O) Cn1cnc2ccccc12) c1cccc (F) c1) C (=O) NC1CCCC1

Molecular Formula

C29H30ClFN4O2

Molecular Weight

521.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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