MHC Class 2, I-A (FITC)
Product Specifications
NCBI Gene ID
100125825
Reactivity
Mouse, Rat
Storage Conditions
-20 °C
Specificity
Recognizes a polymorphic determinant of rat Ia antigen present on Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains (1,2). The antibody crossreacts with mouse strains (MHC haplotypes b and s) and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. It recognizes la antigens on B-cells, dendritic cells and certain epithelial cells (1, 3, 4). It is particularly useful for distinguishing la positive cells from different rat strains, eg for recognizing cells of donor origin in bone marrow reconstituted radiation chimeras (3,4.
Other Gene Names
[orla-uaa]
Short Name
[MHC Class 2, I-A]
Other Product Names
[Mhc class I A; Mhc class I A]
NCBI GI Number
157311697
NCBI Accession Number
NP_001098573.1
NCBI GB Accession Number
NM_001105103.1
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