Tunicamycin 14:1 Mixture

Tunicamycin 14:1 is a mixture of isomers featuring a 14-carbon branched N-acyl chain derived from cellular BCFAs, which dictates its bioactivity. The purified iso-branched form is a potent inhibitor of the bacterial enzyme MraY (IC50 = 0.31 μM) . This compound is widely used in research to study bacterial cell wall biosynthesis, protein N-glycosylation, and endoplasmic reticulum stress in various experimental models.