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JJH260

JJH260 is a potent inhibitor of the FAHFA hydrolase AIG1 (IC50 = 0.57 μM against 9-PAHSA hydrolysis) and also targets ADTRP, ABHD6, LYPLA1, and LYPLA2. This cell-permeable compound effectively blocks FAHFA hydrolase activity in lysates and intact cells, such as LNCaP and T cells, making it a valuable chemical probe for studying lipid signaling in metabolic and immunological research.

Product Specifications

CAS Number

1831135-30-8

Field of Research

Metabolism Research

Smiles

O=C1C2N (C (=O) N1OC (=O) N3CCC (CCC4=CC=C (Cl) C=C4) CC3) CCN (C (=O) C5=CC=C (N (C) C) C=C5) C2

Molecular Formula

C29H34ClN5O5

Molecular Weight

568.06

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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