JJH260
JJH260 is a potent inhibitor of the FAHFA hydrolase AIG1 (IC50 = 0.57 μM against 9-PAHSA hydrolysis) and also targets ADTRP, ABHD6, LYPLA1, and LYPLA2. This cell-permeable compound effectively blocks FAHFA hydrolase activity in lysates and intact cells, such as LNCaP and T cells, making it a valuable chemical probe for studying lipid signaling in metabolic and immunological research.
Product Specifications
CAS Number
1831135-30-8
Field of Research
Metabolism Research
Smiles
O=C1C2N (C (=O) N1OC (=O) N3CCC (CCC4=CC=C (Cl) C=C4) CC3) CCN (C (=O) C5=CC=C (N (C) C) C=C5) C2
Molecular Formula
C29H34ClN5O5
Molecular Weight
568.06
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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