RMC-0331
RMC-0331 (RM-023) is a potent, orally bioavailable SOS1 inhibitor that exhibits anticancer potential by disrupting the RAS-SOS1 interaction to block RAS activation. It is a valuable research tool for investigating RAS-driven cancers in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2488788-52-7
Product Name Alternative
RM-023, RMC 0331, RMC0331, RMC-0331, SOS1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.84% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8 mM) ; DMSO:100 mg/mL (200.04 mM)
Smiles
COC1 (CCOCC1) C (=O) N1Cc2nc (Cl) nc (N[C@H] (C) c3cc (N) cc (c3) C (F) (F) F) c2C1
Molecular Formula
C22H25ClF3N5O3
Molecular Weight
499.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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