R 121919 hydrochloride
This orally bioavailable small molecule is a potent and selective CRF1 receptor antagonist (Ki = 3.5 nM) . It effectively inhibits stress-induced ACTH release in vivo and demonstrates anxiolytic and antidepressant properties in animal models, making it a valuable research tool for studying stress-related disorders.
Product Specifications
CAS Number
195055-66-4
Field of Research
Pharmacology & Drug Discovery
Smiles
Cl.CCCN (CCC) c1cc (C) nc2c (c (C) nn12) -c1cnc (cc1C) N (C) C
Molecular Formula
C22H33ClN6
Molecular Weight
417.0
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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