SP 600125, negative control
SP 600125 negative control is a methylated analog serving as a negative control for the JNK inhibitor SP 600125. It inhibits the DTP3 and GADD45β/MKK7 complex, restoring pathway activation, and exhibits IC50 values of 18 μM and 24 μM against JNK2 and JNK3, respectively. This compound is a valuable tool for validating JNK-related signaling mechanisms in both cellular and biochemical assays.
Product Specifications
CAS Number
54642-23-8
Product Name Alternative
GADD45β/MKK7, JNK3, JNK Inhibitor II, negative control, JNK2, SP 600125, negative control
Field of Research
Cell Biology, Signal Transduction
Purity
≥98% (May vary between batches)
Solubility
DMSO:9 mg/mL (38.42 mM)
Smiles
O=C1C=2C=3C (C=4C1=CC=CC4) =NN (C) C3C=CC2
Molecular Formula
C15H10N2O
Molecular Weight
234.25
Storage Conditions
-20°C
Notes
For research use only.
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