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CU-32

CU-32 is a selective cGAS inhibitor (IC50=0.45 μM) that suppresses DNA-induced IFN-β production in THP-1 cells without affecting RIG-I or TLR pathways. This tool compound is used in vitro to study the cGAS-STING signaling axis in autoimmunity, viral infection, and cancer-related inflammation research.

Product Specifications

CAS Number

2400954-16-5

Field of Research

Immunology & Inflammation

Smiles

N (C=1N=C (C (OC) =O) N=C (N) N1) C2=CC=C (I) C=C2

Molecular Formula

C11H10IN5O2

Molecular Weight

371.13

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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