CU-32
CU-32 is a selective cGAS inhibitor (IC50=0.45 μM) that suppresses DNA-induced IFN-β production in THP-1 cells without affecting RIG-I or TLR pathways. This tool compound is used in vitro to study the cGAS-STING signaling axis in autoimmunity, viral infection, and cancer-related inflammation research.
Product Specifications
CAS Number
2400954-16-5
Field of Research
Immunology & Inflammation
Smiles
N (C=1N=C (C (OC) =O) N=C (N) N1) C2=CC=C (I) C=C2
Molecular Formula
C11H10IN5O2
Molecular Weight
371.13
Storage Conditions
-20°C
Notes
For research use only.
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