Nexinhib20
Nexinhib20 is a small molecule inhibitor of exosome biogenesis and transport, targeting RAB27A and nSMase2. It exhibits anti-inflammatory activity by suppressing neutrophil adhesion and β2 integrin activation through Rac1-GTP interaction antagonism, as demonstrated in vitro with human neutrophils.
Product Specifications
CAS Number
331949-35-0
Product Name Alternative
Nexinhib20, Nexinhib-20
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.89% (May vary between batches)
Solubility
Ethanol:5 mg/mL (16.65 mM) ; DMSO:80 mg/mL (266.39 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (10.99 mM)
Smiles
O=C (C (C) (C) C) C (N1N=CN=C1) =CC2=CC=CC ([N+] ([O-]) =O) =C2
Molecular Formula
C15H16N4O3
Molecular Weight
300.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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