Patulin
Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage[1][2][3][4].
Product Specifications
CAS Number
149-29-1
Product Name Alternative
Terinin
UNSPSC
12352005
Hazard Statement
H300, H315
Target
Antibiotic; Apoptosis; Autophagy; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Autophagy
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/patulin.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic; warming)
Smiles
O=C1OC2=CCOC(C2=C1)O
Molecular Formula
C7H6O4
Molecular Weight
154.12
Precautions
H300, H315
References & Citations
[1]Puel O, et al. Biosynthesis and toxicological effects of patulin. Toxins (Basel) . 2010 Apr;2 (4) :613-31.|[2]Glaser N, et al. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50 (5) :1796-801.|[3]Sun M, et al. Patulin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis and Impaired Mitophagy in HepG2 Cells. J Agric Food Chem. 2018 Nov 21;66 (46) :12376-12384.|[4]Glaser N, et al. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50 (5) :1796-801.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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