GABA Receptor A, gamma 2 (GAG2)

May be stored at 4 °C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 °C. Aliquots are stable for at least 12 months at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Recognizes GABA receptor A, Gama 2. The 30 AA rat control peptide is 100% conserved in bovine, human and mouse GAG2 (2). It is ~80% conserved in chicken GAB2. Significant homology is also seen with rat GAG1 (64%), ratGAG3 (55%). It is not clear if anti-GAG21 actually reacts with other gamma subunits. No significant homology is observed with other GAA subunits (alpha, beta etc.). Antibody crossreactivity of anti-GAG21 in various species has also not been studied.

[gamma-aminobutyric acid receptor subunit gamma-2 isoform 2; Gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid receptor subunit gamma-2; OTTHUMP00000160873; OTTHUMP00000160874; OTTHUMP00000224398; OTTHUMP00000224400; GABA(A) receptor subunit gamma-2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA(A) receptor subunit gamma-2]