ROC-0929
ROC-0929 is a potent and selective small molecule inhibitor of secreted phospholipase A2 (sPLA2), particularly human group X (hGX), with an IC50 of 80 nM. It effectively suppresses downstream MAPK signaling, including ERK1/2 and p38 phosphorylation, making it a valuable research tool for investigating sPLA2-driven inflammatory processes in both cellular and animal models.
Product Specifications
CAS Number
1048660-43-0
Field of Research
Metabolism Research
Smiles
CC (C) Cc1c (C (=O) C (N) =O) c2c (OC (C) C (=O) NS (=O) (=O) c3ccccc3) cccc2n1Cc1ccccc1
Molecular Formula
C30H31N3O6S
Molecular Weight
561.65
Storage Conditions
-20°C
Notes
For research use only.
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