Tanimilast
Tanimilast (CHF-6001) is a highly selective phosphodiesterase 4 (PDE4) inhibitor with sub-nanomolar potency, demonstrated by an IC50 of 0.026 nM. It exhibits robust anti-inflammatory effects and is developed for inhaled administration in obstructive lung diseases, supported by both in vitro and in vivo preclinical research.
Product Specifications
CAS Number
1239278-59-1
Product Name Alternative
PDE4, CHF6001, CHF-6001, CHF 6001, Tanimilast
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.30% (May vary between batches)
Solubility
DMSO:50 mg/mL (72.72 mM)
Smiles
[C@@H] (CC=1C (Cl) =CN (=O) =CC1Cl) (OC (=O) C2=CC (OCC3CC3) =C (NS (C) (=O) =O) C=C2) C4=CC (OCC5CC5) =C (OC (F) F) C=C4
Molecular Formula
C30H30Cl2F2N2O8S
Molecular Weight
687.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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