GSK143
GSK143 is a potent, selective, and orally bioavailable SYK inhibitor (pIC50 7.5) that also suppresses pErk (pIC50 7.1) . It demonstrates anti-inflammatory activity in vivo by reducing immune cell infiltration in mouse intestinal muscularis, making it a valuable tool for researching SYK-related pathways in immunology and inflammation models.
Product Specifications
CAS Number
1240390-27-5
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
Cc1ccc (Nc2nc (N[C@@H]3CCOC[C@@H]3N) ncc2C (N) =O) cc1
Molecular Formula
C17H22N6O2
Molecular Weight
342.403
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog