PugNAc
(Z) -PUGNAc is a cell-permeable, potent and selective inhibitor of O-GlcNAcase (OGA), the enzyme that removes O-GlcNAc modifications from proteins. Its application in both in vitro and in vivo studies effectively elevates global O-GlcNAcylation levels, making it a valuable tool for researching nutrient sensing, cellular stress, and signaling pathways in models of diabetes, neurodegeneration, and cancer.
Product Specifications
CAS Number
132489-69-1
Product Name Alternative
(Z) PUGNAc, (Z) PUGNAc, O-GlcNAcase, PUGNAc
Purity
>98%
Bioactivity
O-GlcNAcase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 35 mg/ml)
Smiles
CC (=O) NC1C (O) C (O) C (CO) OC1=NOC (=O) Nc1ccccc1
Molecular Formula
C15H19N3O7
Molecular Weight
353.33
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
O- (2-Acetamido-2-deoxy-D-glucopyranosylidene) amino-Z-N-phenylcarbamate
Available Sizes
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