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ONO-8430506

ONO-8430506 is a potent and orally bioavailable inhibitor of autotaxin (ATX/ENPP2), demonstrating an IC90 of 100 nM. It effectively suppresses ATX activity in mouse plasma and is a valuable research tool for investigating lysophosphatidic acid (LPA) signaling in cancer, fibrosis, and inflammation research, both in vitro and in vivo.

Product Specifications

CAS Number

1354805-08-5

Product Name Alternative

ONO8430506, ONO-8430506, ONO 8430506, enpp, ATX (autotaxin)

Field of Research

Metabolism Research

Purity

97.05% (May vary between batches)

Solubility

DMSO:90 mg/mL (195 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.15 mM)

Smiles

OC (=O) C12CCC (CC (=O) N3CCc4c (C3) n (Cc3ccc (F) cc3) c3ncccc43) (CC1) C2

Molecular Formula

C27H28FN3O3

Molecular Weight

461.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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