ONO-8430506
ONO-8430506 is a potent and orally bioavailable inhibitor of autotaxin (ATX/ENPP2), demonstrating an IC90 of 100 nM. It effectively suppresses ATX activity in mouse plasma and is a valuable research tool for investigating lysophosphatidic acid (LPA) signaling in cancer, fibrosis, and inflammation research, both in vitro and in vivo.
Product Specifications
CAS Number
1354805-08-5
Product Name Alternative
ONO8430506, ONO-8430506, ONO 8430506, enpp, ATX (autotaxin)
Field of Research
Metabolism Research
Purity
97.05% (May vary between batches)
Solubility
DMSO:90 mg/mL (195 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.15 mM)
Smiles
OC (=O) C12CCC (CC (=O) N3CCc4c (C3) n (Cc3ccc (F) cc3) c3ncccc43) (CC1) C2
Molecular Formula
C27H28FN3O3
Molecular Weight
461.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog