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THI0019

THI0019 is a potent small molecule agonist of the integrin α4β1 (VLA-4), exhibiting an EC50 of 1-2 μM to promote stem/progenitor cell adhesion. It also modulates adhesion mediated by α4β7, α5β1, and αLβ2 integrins, making it a useful research tool for studying cell migration and homing in both in vitro and in vivo immunological and hematopoietic models.

Product Specifications

CAS Number

1378532-99-0

Smiles

CCCC[C@@H] (COC (=O) N (Cc1cccs1) Cc1cccs1) NC (=O) N[C@@H] (CC (=O) OC) c1ccc2OCOc2c1

Molecular Formula

C29H35N3O7S2

Molecular Weight

601.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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