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Sulfo-DGN462 sodium

Sulfo-DGN462 sodium is a prodrug that converts to the active DNA-alkylating agent DGN462 in physiological conditions. DGN462 demonstrates potent anti-tumor activity, particularly in acute myeloid leukemia (AML) research, with efficacy shown in both in vitro cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

1401203-09-5

Field of Research

Molecular Biology

Smiles

[Na].[H][C@@]12Cc3ccccc3N1C (=O) c1cc (OC) c (OCc3cc (COc4cc5NC ([C@]6 ([H]) Cc7ccccc7N6C (=O) c5cc4OC) S (O) (=O) =O) cc (c3) N (CCOCCOCCOC) CC (C) (C) S) cc1NC2

Molecular Formula

C53H60N5NaO12S2

Molecular Weight

1046.19

Storage Conditions

-20°C

Notes

For research use only.

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