MK-8262
MK-8262 is a potent, orally bioavailable CETP inhibitor with an IC50 of 53 nM. This bistrifluoromethyl-substituted compound is utilized in cardiovascular research to study the modulation of HDL and LDL cholesterol levels, with applications in both in vitro and in vivo models of atherosclerosis.
Product Specifications
CAS Number
1432054-03-9
Field of Research
Metabolism Research
Smiles
[H][C@@]12CC[C@H] (N1C (=O) O[C@@H]2c1cc (cc (c1) C (F) (F) F) C (F) (F) F) c1cc (ccc1-c1cc (cnc1OC) -c1ccc (cc1C) C (O) =O) C (F) (F) F
Molecular Formula
C35H25F9N2O5
Molecular Weight
724.58
Storage Conditions
-20°C
Notes
For research use only.
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