AEF0117
Product Specifications
CAS Number
[1610878-71-1]
UNSPSC Description
AEF0117 is a signaling-specific inhibitor of the cannabinoid receptor 1 (CB1-SSi). AEF0117 plays an important role in Cannabis use disorder (CUD)[1].
Target Antigen
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aef0117.html
Solubility
DMF : 10 mg/mL (ultrasonic)|DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OCC4=CC=C(C=C4)OC)([H])[C@@]5([H])[C@](CC3)([C@H](CC5)C(C)=O)C
Molecular Weight
436.63
References & Citations
[1]Margaret Haney, et al. Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials. Nat Med. 2023 Jun;29(6):1487-1499.
Shipping Conditions
Room Temperature
Clinical Information
Phase 2
Available Sizes
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