RORγt inhibitor 1
RORγt inhibitor 1 is a potent and selective allosteric inhibitor of the RORγt nuclear receptor, exhibiting an IC50 of 1 nM. This small molecule is a valuable research tool for studying Th17 cell biology and has been utilized in both cellular assays and in vivo models of autoimmune and inflammatory diseases.
Product Specifications
CAS Number
1561770-72-6
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O[C@@H]1CN (CC[C@H]1C (O) =O) c1nn (C (=O) c2c (Cl) cccc2C2CC2) c2cccc (F) c12
Molecular Formula
C23H21ClFN3O4
Molecular Weight
457.89
Storage Conditions
-20°C
Notes
For research use only.
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