MK-4688
MK-4688 is a potent and selective small molecule inhibitor that disrupts the HDM2-p53 protein-protein interaction. It is utilized in cancer research to reactivate p53 tumor suppressor pathways, with applications in both in vitro biochemical assays and in vivo xenograft studies.
Product Specifications
CAS Number
1616428-79-5
Field of Research
Cell Biology
Smiles
[H][C@@]12CCC[C@@]1 ([H]) N (CCO2) c1nc2cc (nc (-c3cncc (Cl) c3) c2n1C[C@H]1CC[C@H] (C) CC1) -c1noc (=O) [nH]1 |wU:5.6,28.32, wD:1.0,31.36, (-.16,3.07, ; ,1.54, ; -1.46,2.02, ; -2.37, .77, ; -1.46, -.48, ; ; -.16, -1.53, ;1.33, -.77, ;2.67, , ;2.67,1.54, ;1.33,2.31, ;1.33, -2.31, ; .09, -3.22, ; .56, -4.68, ; -.21, -6.01, ; .56, -7.35, ;2.1, -7.35, ;2.87, -6.01, ;4.41, -6.01, ;5.18, -4.68, ;6.72, -4.68, ;7.49, -6.01, ;6.72, -7.35, ;7.49, -8.68, ;5.18, -7.35, ;2.1, -4.68, ;2.58, -3.22, ;4.04, -2.74, ;4.36, -1.23, ;3.22, -.2, ;3.54,1.3, ;5,1.78, ;5.32,3.29, ;6.15, .75, ;5.83, -.76, ; -.21, -8.68, ; -1.74, -8.84, ; -2.06, -10.35, ; -.72, -11.12, ; -.56, -12.65, ; .42, -10.09, ) |
Molecular Formula
C28H32ClN7O3
Molecular Weight
550.06
Storage Conditions
-20°C
Notes
For research use only.
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