Zunsemetinib
Zunsemetinib (ATI-450) is an oral, selective inhibitor targeting the p38α/MK2 pathway. It is utilized in preclinical research for inflammatory diseases such as rheumatoid arthritis and spondyloarthritis, with studies demonstrating its activity in both cellular and animal models of these conditions.
Product Specifications
CAS Number
1640282-42-3
Product Name Alternative
MK2, CDD 450, CDD450, CDD-450, ATI450, ATI-450, ATI 450, Zunsemetinib
Field of Research
Signal Transduction
Purity
99.77% (May vary between batches)
Solubility
DMSO:80 mg/mL (155.67 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.42 mM)
Smiles
Cc1cnc (cc1-n1c (C) cc (OCc2ncc (F) cc2F) c (Cl) c1=O) -c1ccnc (n1) C (C) (C) O
Molecular Formula
C25H22ClF2N5O3
Molecular Weight
513.92
Storage Conditions
-20°C
Notes
For research use only.
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