BMS-986143
BMS-986143 is a potent, reversible, and orally bioavailable BTK inhibitor (IC50=0.26 nM) developed for autoimmune disease research. It also potently inhibits related kinases like TEC, BLK, and ITK. This profile supports its use in both in vitro biochemical assays and in vivo models of B-cell mediated inflammatory conditions.
Product Specifications
CAS Number
1643372-95-5
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
ClC=1C (=C2C (=C (C (N) =O) C1) NC=3C2=CC=C (C (C) (C) O) C3) C4=C (C) C (=CC=C4) N5C (=O) N6C (=CC5=O) C (Cl) =CC=C6
Molecular Formula
C31H24Cl2N4O4
Molecular Weight
587.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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