GS-493
GS-493 is a potent and selective SHP2 (PTPN11) inhibitor with an IC50 of 71 nM, showing strong selectivity over SHP1 and PTP1B. It has demonstrated antitumor activity in research by inhibiting cancer cell proliferation and migration in vitro, supporting its investigation in oncology and signaling pathway studies.
Product Specifications
CAS Number
1710337-31-7
Field of Research
Metabolism Research
Smiles
OS (=O) (=O) c1ccc (N\N=C2/C (=O) N (N=C2c2ccc (cc2) N (=O) =O) c2ccc (cc2) N (=O) =O) cc1 |c:14|
Molecular Formula
C21H14N6O8S
Molecular Weight
510.44
Storage Conditions
-20°C
Notes
For research use only.
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