Thalidomide-O-amido-C3-PEG3-C1-NH2
This compound is a cereblon (CRBN) -directed E3 ligase ligand-linker conjugate, incorporating a thalidomide-based ligand connected via a triethylene glycol spacer. It is a key component for constructing PROTACs, bifunctional molecules used in chemical biology and drug discovery research to induce targeted protein degradation in both cellular and in vivo models.
Product Specifications
CAS Number
1799711-29-7
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology
Smiles
OC (=O) C (F) (F) F.NCCCOCCOCCOCCCNC (=O) COc1cccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c12
Molecular Formula
C27H35F3N4O11
Molecular Weight
648.589
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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