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Mc-VC-PAB-SN38

Mc-VC-PAB-SN38 is a cleavable linker-payload conjugate used in the synthesis of antibody-drug conjugates (ADCs) . This construct enables targeted delivery of the potent topoisomerase I inhibitor SN38, facilitating research into ADC efficacy and mechanism in both in vitro and in vivo cancer models.

Product Specifications

CAS Number

1801838-28-7

Product Name Alternative

DrugLinkerConjugatesforADC, DrugLinker Conjugates for ADC, Antibody-Drug Conjugates (ADCs), Mc VC PAB SN38, McVCPABSN38, Mc-VC-PAB-SN38, Mc-VC-PAB-SN-38

Purity

98.59% (May vary between batches)

Solubility

DMSO:50 mg/mL (50.45 mM)

Smiles

CCc1c2Cn3c (cc4c (COC (=O) [C@@]4 (CC) OC (=O) OCc4ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCCCCN5C (=O) C=CC5=O) C (C) C) cc4) c3=O) -c2nc2ccc (O) cc12

Molecular Formula

C51H58N8O13

Molecular Weight

991.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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