Mc-VC-PAB-SN38
Mc-VC-PAB-SN38 is a cleavable linker-payload conjugate used in the synthesis of antibody-drug conjugates (ADCs) . This construct enables targeted delivery of the potent topoisomerase I inhibitor SN38, facilitating research into ADC efficacy and mechanism in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
1801838-28-7
Product Name Alternative
DrugLinkerConjugatesforADC, DrugLinker Conjugates for ADC, Antibody-Drug Conjugates (ADCs), Mc VC PAB SN38, McVCPABSN38, Mc-VC-PAB-SN38, Mc-VC-PAB-SN-38
Purity
98.59% (May vary between batches)
Solubility
DMSO:50 mg/mL (50.45 mM)
Smiles
CCc1c2Cn3c (cc4c (COC (=O) [C@@]4 (CC) OC (=O) OCc4ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCCCCN5C (=O) C=CC5=O) C (C) C) cc4) c3=O) -c2nc2ccc (O) cc12
Molecular Formula
C51H58N8O13
Molecular Weight
991.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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