Milvexian
Milvexian (BMS-986177) is an orally bioavailable, potent, and reversible direct inhibitor of factor XIa (FXIa) . It demonstrates high affinity with Ki values of 0.11 nM (human) and 0.38 nM (rabbit), supporting its investigation in antithrombotic research for both in vitro enzymatic studies and in vivo preclinical models.
Product Specifications
CAS Number
1802425-99-5
Field of Research
Metabolism Research
Purity
99.91% (May vary between batches)
Smiles
C (F) (F) N1C=2C=3C=C ([C@H] (CCC[C@@H] (C) C (=O) NC2C=N1) N4C (=O) C=C (N=C4) C5=C (C=CC (Cl) =C5) N6C=C (Cl) N=N6) N=CC3
Molecular Formula
C28H23Cl2F2N9O2
Molecular Weight
626.45
Storage Conditions
-20°C
Notes
For research use only.
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