YNT-185
YNT-185 is a potent and selective nonpeptide agonist for the orexin-2 receptor (OX2R), with an EC50 of 0.028 μM, showing over 98-fold selectivity over OX1R. It has demonstrated efficacy in alleviating narcolepsy-cataplexy symptoms in mouse models, making it a valuable tool for in vivo sleep/wake regulation research and in vitro OX2R signaling studies.
Product Specifications
CAS Number
1804978-81-1
Product Name Alternative
OX2, OX Receptor, OXReceptor, YNT 185, YNT185, YNT-185
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.60% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (4.06 mM) ; DMSO:62 mg/mL (100.69 mM) ; H2O:Insoluble
Smiles
S (NC1=CC (NCCNC (=O) C2=C (N (C) C) C=CC=C2) =CC=C1) (=O) (=O) C3=C (OC) C=CC (=C3) C4=CC (C (N (C) C) =O) =CC=C4
Molecular Formula
C33H37N5O5S
Molecular Weight
615.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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