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PF-06426779

PF-06426779 is a highly potent and selective small molecule inhibitor of IRAK4, demonstrating an IC50 of 0.3 nM. It is a valuable research tool for studying TLR/IL-1R signaling in autoimmune and inflammatory diseases, applicable in both cellular and animal models.

Product Specifications

CAS Number

1817628-40-2

Field of Research

Immunology & Inflammation, Signal Transduction

Smiles

COc1cc2c (OC[C@H]3NC (=O) [C@@H] (F) [C@H]3C) nccc2cc1C (N) =O

Molecular Formula

C17H18FN3O4

Molecular Weight

347.346

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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