PF-06426779
PF-06426779 is a highly potent and selective small molecule inhibitor of IRAK4, demonstrating an IC50 of 0.3 nM. It is a valuable research tool for studying TLR/IL-1R signaling in autoimmune and inflammatory diseases, applicable in both cellular and animal models.
Product Specifications
CAS Number
1817628-40-2
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
COc1cc2c (OC[C@H]3NC (=O) [C@@H] (F) [C@H]3C) nccc2cc1C (N) =O
Molecular Formula
C17H18FN3O4
Molecular Weight
347.346
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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