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Tri-GalNAc-COOH

Tri-GalNAc-COOH is a high-affinity ligand for the hepatic asialoglycoprotein receptor (ASGPR) . It is widely utilized in LYTAC development for targeted protein degradation, enabling both in vitro and in vivo research into lysosomal trafficking pathways.

Product Specifications

CAS Number

1953146-81-0

Product Name Alternative

Tri GalNAc COOH, triGalNAcCOOH, tri-GalNAc-COOH, LYTACs

Field of Research

Pharmacology & Drug Discovery

Purity

99.13% (May vary between batches)

Solubility

DMSO:225 mg/mL (129.62 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (2.88 mM) ; H2O:20 mg/mL (11.52 mM)

Smiles

CC (=O) N[C@@H]1[C@@H] (O) [C@@H] (O) [C@@H] (CO) O[C@H]1OCCCCC (=O) NCCCNC (=O) CCOCC (COCCC (=O) NCCCNC (=O) CCCCO[C@@H]1O[C@H] (CO) [C@H] (O) [C@H] (O) [C@H]1NC (C) =O) (COCCC (=O) NCCCNC (=O) CCCCO[C@@H]1O[C@H] (CO) [C@H] (O) [C@H] (O) [C@H]1NC (C) =O) NC (=O) CCOCCOCCOCCOCCOCCC (O) =O

Molecular Formula

C75H134N10O35

Molecular Weight

1735.91

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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