PNU-EDA-Gly5
PNU-EDA-Gly5 is a conjugate comprising the potent topoisomerase I inhibitor PNU-159682 linked via an EDA-Gly5 spacer, designed for constructing antibody-drug conjugates (ADCs) . This payload-linker system is utilized in ADC research for targeted cancer therapy, demonstrating potent antitumor activity in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1957223-28-7
Field of Research
Stem Cell & Developmental Biology
Smiles
[H][C@]12C[C@H] (O[C@H]3C[C@@] (O) (Cc4c (O) c5C (=O) c6cccc (OC) c6C (=O) c5c (O) c34) C (=O) NCCNC (=O) CNC (=O) CNC (=O) CNC (=O) CNC (=O) CN) O[C@@H] (C) [C@@]1 ([H]) O[C@]1 ([H]) [C@@H] (OC) OCCN21
Molecular Formula
C43H54N8O17
Molecular Weight
954.944
Storage Conditions
-20°C
Notes
For research use only.
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