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(±) -LY367385

LY367385 is a potent and selective mGluR1a antagonist, with its racemic form designated (±) -LY367385. It inhibits quisqualate-induced PI hydrolysis (IC50 = 8.8 μM) and shows >100-fold selectivity over mGlu5a. This compound is widely used in vitro and in vivo to study mGluR1's role in neurological functions and disorders.

Product Specifications

CAS Number

198419-90-8

Field of Research

Neuroscience

Smiles

Cc1cc (ccc1C (N) C (O) =O) C (O) =O

Molecular Formula

C10H11NO4

Molecular Weight

209.201

Storage Conditions

-20°C

Notes

For research use only.

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