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Aclimostat

Aclimostat (ZGN-1061) is a potent MetAP2 inhibitor with promising preclinical efficacy and safety. It demonstrates significant weight loss and metabolic improvement in murine obesity models, comparable to beloranib, and induces consistent transcriptional changes in HepG2 cells, supporting its role in metabolic disease research.

Product Specifications

CAS Number

2082752-83-6

Field of Research

Metabolism Research

Smiles

[H][C@@]1 ([C@H] (OC) [C@@H] (CC[C@]11CO1) OC (=O) N1CC (CCN2CCOCC2) C1) [C@@]1 (C) O[C@@H]1CC=C (C) C

Molecular Formula

C26H42N2O6

Molecular Weight

478.63

Storage Conditions

-20°C

Notes

For research use only.

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